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Frequency Comb Technology combined with ML to check your health condition

Frequency Comb Technology combined with ML to check your health condition

Technology News |
By Wisse Hettinga



JILA researchers have upgraded a breathalyzer based on Nobel Prize-winning frequency-comb technology and combined it with machine learning

Frequency comb technology has the potential to non-invasively diagnose more health conditions than other breath analysis techniques while also being faster and potentially more accurate than some other medical tests. Frequency combs act as rulers for precisely measuring different colors of light, including the infrared light absorbed by molecules.

Human breath contains more than 1,000 different trace molecules, many of which are correlated with specific health conditions. JILA’s frequency comb breathalyzer identifies chemical signatures of molecules based on exact colors and amounts of infrared light absorbed by a sample of exhaled breath.

Back in 2008, JILA demonstrated the world’s first frequency comb breathalyzer, which measured the absorption of light in the near-infrared part of the optical spectrum. In 2021 they achieved a thousandfold improvement in detection sensitivity by extending the technique to the mid-infrared spectral region, where molecules absorb light much more strongly. This enables some breath molecules to be identified at the parts-per-trillion level where those with the lowest concentrations tend to be present.

Find more on the frequency comb technology used for health diagnosis at the NIST website

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